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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10edec5e1d21c7105faf5bb2ff316653a729fc83065ec5319a2530c9ceb48810' 
  AND token = 'Fu1adILvT4bXF2TeoeifB9u21HqUMtBHGXgYFPXOtk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}