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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c2db5ec7c081202bd6b68c689729f6caedf190aa26aff3a6e28e7a6253b366' 
  AND token = 'Y4jkPVpvvbp0V4E1gWMlmtOTubcPT7pPMVUDcplRsFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}