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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10bf9072ef822cf26c34cd7b32cd4f031ded1d1120e4a806915767f0e59b0211' 
  AND token = '2qKeWR5Orh1g+j2UgH2LTpsheG+sAuFWX6IexfGFwn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}