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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5037b1fa39cb8cf7a45447f9f10b58dd4e54e8044af5336833696fbc3a3c4f74' 
  AND token = 'Fs/omXexbBsidiEbcWT+3DYjLKH2EvLL/aSKJXpTiTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}