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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d5048445dfb017dd21e0d103d27c68eea168f296304c39c91108c44c21817d4' 
  AND token = 'L01+CwblBZTBhyEF3rKOYsm0pOsAbHHucjAfhcgrzGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}