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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e862fd61a17158fc051a1ae2a88eea8492c4df351262f0d406023222c67d0cb1' 
  AND token = 'r974YMP/DTnndqGkhvawinS9qwDIIjPRnLLZpns4jtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}