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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21dfeed0492c6be552630256f86f6a5d0f196aaead093fd1f4a4c51d30c4f25' 
  AND token = 'ykFJd9ircPhry6707SpeMb8gxP9R6KYGNPT3Y6Umpi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}