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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a891aff08661e94dd13637ea200e5c92bd492baeece7408439eaf827e275d90' 
  AND token = 'n/vZdPnx69BfckA9+qoRXkGwcBHp2AkXLPEBjEA8CUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}