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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8862b3526f9a6b73bc0b2ec4ce81c2ba7d60b9c66a1553195039e9c555552d' 
  AND token = 'iH46uiV3bF2EslGGOdWhTIJD8+XMlFKa+62elZ94Zdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}