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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '440664e08b0632b366aa75a710e55b7b682cef99b271f3c672bbd4ad97a18d1f' 
  AND token = 'Sm8MdjF181koK48ziXDytKOJEPNQiRCdQczM9drruAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}