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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba7b00a626bc292e9a58231b446671a9bfd5e5f522e3b50bf357e1f1e74f581f' 
  AND token = 'Wia3wjivmnpCtvtVsIBOTzY3bDZSCyyM1KYrIjLj2Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}