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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a773d4983bf76ce35299ba047f75778da6a2a7d7838caf4694b90dc441a0221c' 
  AND token = '1Lm7XKnOVv+meV1/+PRd+Z2BaI3rtQVAkPSv5LH/fNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}