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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4c83d82bd387511a8d71d71fb3bc28248a184a3df178134e43dbf20dbde07a' 
  AND token = 'iBX0g9cRxjrv9fT7i0L0G66565PUFB2fmnY4/jGLMZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}