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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06404f1612d50a23da7212c2683d524153009a503c4c1e5e85761e9c6b9eb2c7' 
  AND token = 'kQHmerOCPm/RDu4IhI1xCUAef7m/VYteNIwh5ZxE04I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}