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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '681fd888ccf868fd0b989f2023c6a13c40b92ef45aa1c991b3633badbd97387f' 
  AND token = 'xw6oHzcEK+bsHN+lyL5D+acUesC0EMtKn3vFuj9VTQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}