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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72588bd3de21aebca32ca34f1817f600157ab94674b80ab11a77b3b99a8fca15' 
  AND token = 'OQFiBh84XOpBC5OrXK5cK5/7lnSOJtrqSY8Y0Uy5CrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}