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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bf45918fb0ee6a8be6a30faa9b39b933207b4061f0558f4a2c34e07f0be1586' 
  AND token = 'qCK0x7IGysxe/+MvbbUjI8kN06NHDVammIjo4BYdZOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}