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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f9defda99a1b4b46f35a5d6adf2a48675ba59a78f9d8802a47e508674f49d5' 
  AND token = 'BeH9tjiqATBZdXyjDgxnHx9VFEjYOXfo+2WUPDMQ7ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}