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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c08ebc456b9dee84410c089ed9bee48bacc8a5c9627d23574bb6522c2f0841' 
  AND token = 'PA8NVwUhtGIx1BxTQ6HG4Ta+KvxEy7Gj4RVvhRXSmI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}