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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ac0755502760b007f8bfac4d895300d986d9c4b3f50063353d2f5a24ede491' 
  AND token = 'H0AueUVMJwUJBMor6VNOxfdG1I+NjfKjieUzYvu7qEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}