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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '700dc5bbd0ac7b3ad97e372c6bcf9b010017c3c2300a1855634ddbf0f355f0f2' 
  AND token = 'GoxycwEMDEk/jb6s7YgNJWaYSuCSstf2qxlVnE2qhd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}