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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f9146a6c50027e1349e63ef17ff05c4d44e6bb6ad6746ca8f766190203d391' 
  AND token = 'mJz9Ob8NLS7VUOR0VLO4P+JDR1sUdL2PwWcNggM+hnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}