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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f448d6f2bc3582f3761838d973b11498e875c993cdc1d27c8bcaef23522d57cb' 
  AND token = '5xpcRxOEt1X4VpF1RmYyF2XfjecUckQpLtt+PXAPrlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}