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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f454b1e21ea7ab4d483fa931e9f26bc903ca3b94661721c88d0157603a9b76' 
  AND token = 'hisfmDa5UKL35o5/OTMD3hnjWb71dYd9AeQ2xxZhEds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}