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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8a1d278563309d3662be0f01842d66d937014051b449ca3e85e0aa6d04df39' 
  AND token = 'viGTZo2y/BTLxZ4rqcp0O0+MZeo4rqpIjVDZZ9QvHjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}