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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61652fbfcad2d45a6669ca0d0328f7884ad060a9a9ecaae1abce0744ff395c8d' 
  AND token = 'PPrG81eBHs46X3Dj6bod+YIrfKfehr7a4gvwd+q2GuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}