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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921c4c64f35a4232df7bde1cf6783494d4f81af7fa1c9112a038646eac806d76' 
  AND token = 'E3hu3qa6MeQ800PYyJGLFQCHzFnquN6ANDG18TEnN+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}