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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd78f880b7ef88eaf06d3cb240a65a2afe228ad6119624f38ddb515bf0c1db23' 
  AND token = 'XLoZjwNTQ4eDaVLOk5bKGwuNb2GxvKRmry2tN0bTNxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}