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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd86e203beb4938afda974d1d02868a19722cffc6591ea86b112f2461918094fc' 
  AND token = '48qzB8g42RTaMBFkvD9EVrzCYCQ3QPgnrHHZ3o3X9iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}