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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954bb20097b4e237b0a38db4d8124736e441fe74c19362a738c3d21ced46960f' 
  AND token = 'XktR4kdWkN9lgOqovY5t9O7qkUw6YYUh2YrwYeBLZHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}