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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c5f38b665667370576ab574b36d11b42939b70ebc6450513984b05ad7fcbfe' 
  AND token = 'nK1CGULR3lWqoaaiPhEXbGwP9Dc1P1aQ0epesHLfAS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}