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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2250b9066e94f2dc3469ee6a4f8089115a0b97199837a42c5e0ec8068607734c' 
  AND token = 'Ln+pmAH3ObX6xR3vMeOvx1ChqL+1gOPbsSO1PWsFmNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}