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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b5b1d2dee3dd1d3fbb677330e8ba837c10955840631d684941d6acc26863e3d' 
  AND token = 'eZ1sQCimJTPvpbJQ7Wei/kvwCN6Khkk9Ln7N+YszYDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}