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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c8ecf6a44fc980f9f1be70a1b2fa2b3d518af6a5d313352bf9812c06add2490' 
  AND token = 'MaLDLMyvTxspLX9MQfyYvvnPmMPid4cUob51/Y9j6AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}