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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6000ec64a672e9c690e2e71c5b29aa72de61f5448b761c3c75c290b36f72eddf' 
  AND token = '7Z0AEUmOxsdUjmDacueQpmoYpwC8z/zdkLkoQ4lCQFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}