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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a477f8cd2ca88a4a8b9e97ec4d4eb86fa9e586506e29527f241e367ee76d69' 
  AND token = 'oPo/aiZMayt2OrwIMuyzKGjx0Ye/byCsdtIHNb675OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}