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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '677c7ea997ba3439a3a8ced625e7531d71bc78b10800e6d0e60878cbba517b11' 
  AND token = 'v3LaAEQ2EF0lzUeOo57R5xyMnQEqm4qtIM7VutsmYbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}