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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459041a2be504fc598c94d53e49a2e82f8fe0e55b180858979aa487cffda2fcf' 
  AND token = '0gpNr/CzHt+XvpDJjRzGO2iscB8F7NhzXzE0qssbfCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}