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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e831e79df0816cbefe1b4973fb562011722df80736ada7d0f203b1d03cf6068' 
  AND token = '/i2urgkaL5yFAaOisUlvrySFSlnuHEhvBHqsIAZLtBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}