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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5853962537513f102c26d2c370c3d81391307e6ff362d695486df5baeab5e7' 
  AND token = 'JEH40LoWLCrg7QRpHA/v/QX7HJOziQGrLTnDIGXgcKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}