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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780e0ca1df4f1b7d35934ae7b06282ee97e153da14a3078bc679aefbd1993536' 
  AND token = '0yhY8WXp00C0osccd7uPDTRFaM1Ice88o8UhMaJCPlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}