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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '878b025a3de75a92273d6daf1f697c40f95f2cf91993180fa951f6dc434f6a75' 
  AND token = 'EVQ8ydxzlOByD2iBbDTglC7aDYyITh1DD4SfXpWLMOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}