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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1147ece07db0fab38cffa4af64720924bff14e1b9be6d06b4991e1ab39147e7c' 
  AND token = 'zTjM5bTn54zcnxDHTMcHqxO60VWKO+mmTkSsS0zH2fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}