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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c5cc05f9e5310832d29801982faf2a04c717e729f0149e79ce3860409ff149' 
  AND token = '5MoN4kPHBdCXFo85UpB9pbxAdtnDwmamwGWFJhegowE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}