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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4ac19cf71947a3d346a148429b9372f24d6775edbac7cc101ac2653d9287866' 
  AND token = 'NcoW8fvaFtvbeB/JQywKbkvMrnAL1C2ONi1KzcGT6n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}