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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b00d9d87934bb8275c4947c7ad8398ed28933dd591f30129503f87793289d82' 
  AND token = 't1+5lKT9khhGoFGr41sRa6AThXmKyFLN/gDZwrJpcLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}