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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f053d01ab075a8d473159984fed92b8fe529e8022b24a4f5af20f64eacabd04' 
  AND token = '3rSdn72ym+WfMZ22sYdsC+wJvW/Syo2XtFeAv5xkiVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}