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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c091c985ccfb4debf5bd7e1f0cf148a133797deb0dec041987ca7f5742f653' 
  AND token = 'acn1BhdFiMd83XtiN/lV8dW3mMFJO9lc6b65FbH8VW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}