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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb68e29426209d8688a7f761d23e47ba968821d6aa9a4c176e8b3bd7f05213ef' 
  AND token = 'ysRGu16QbAXwOQZAzmQKw+E6Z6vlXA4GDKsZoxpq0Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}