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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6702d019b1ff89bd10b91f81b24102d1d1814ff3fe1bbe53ef69b9395fe290' 
  AND token = '1E6TFo61EhNPFZHCpjF/6rQtDHhvvbKrHP8HRHOj6yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}